Photodynamic therapy (PDT) is a treatment used mainly for superficial types of skin cancer. PDT is effective in treating actinic keratoses, in situ squamous cell carcinoma (Bowen disease), and superficial basal cell carcinomas. It may also be used for treatment of small, thin, low-risk nodular basal cell carcinomas outside of the head and neck area.
PDT is also sometimes used off-label for facial rejuvenation and to treat mild to moderate acne, and a variety of skin infections including wound infections, onychomycosis, viral warts, and cutaneous leishmaniasis. Several other conditions have also been studied and may respond to PDT such as psoriasis, mycosis fungoides, and extramammary Paget disease.