Patient receiving a neuromodulator treatment at Rejuvenation Dermatology

Boey® is
almost here.

Canada’s first rapid-onset, short-duration neurotoxin for frown lines: results can begin within about 8 hours and fade in 2 to 3 weeks. Join the waitlist for first access.

Join the waitlist → Call (403) 286-6888
Rapid OnsetShort DurationFrown LinesHealth Canada AuthorizedCalgaryEdmontonVancouverOkotoksOakvilleJoin the WaitlistRapid OnsetShort DurationFrown LinesHealth Canada AuthorizedCalgaryEdmontonVancouverOkotoksOakvilleJoin the Waitlist
The Treatment

What is Boey, exactly?

A Boey treatment, start to finish
Hour 0A 10 to 20 minute visit. A few small injections between the brows, then straight back to your day.
Hour 8The earliest point at which a visible change was seen in clinical trials.
Day 7The trials’ primary measurement point: 60% to 66% of patients met the responder threshold by day seven.
Weeks 2 to 3The effect fades on its own and your frown line returns to where it started.
Quick answer: Boey® (trenibotulinumtoxinE) is a Health Canada-authorized injectable neurotoxin for the temporary improvement of moderate to severe frown lines between the eyebrows in adults. It is the first botulinum toxin type E approved anywhere in the world. Results may be visible as early as 8 hours after treatment and typically wear off within two to three weeks.

Like Botox®, Boey works by temporarily relaxing the small muscles that pull the brows together when you frown. The difference is the serotype. Botox, Dysport® and Nuceiva® are all botulinum toxin type A, which takes several days to start working and lasts three to four months. Boey is type E: it is taken up by nerve endings quickly and clears quickly, so the effect arrives sooner and leaves sooner, by design.

That makes Boey a different tool rather than a replacement. Allergan Aesthetics, the makers of both products, describe it as a way to experience what a smoother frown line looks and feels like without a months-long commitment. In its two Phase 3 trials, 60% to 66% of patients reached the responder threshold by day seven, and the most common side effects (headache and injection-site tenderness) were reported no more often than with placebo.

And if you like what you see, the next step is already mapped: Botox Cosmetic® is the only neuromodulator clinically studied for use after Boey, so your injector can plan the transition at the same clinic, with the same team.

8 hrsEarliest visible results
2 to 3Weeks of effect
10 to 20Minute visits
947Patients in Phase 3 trials
Who Boey Is For

A preview, not a commitment.

Boey was designed for people who are curious about neuromodulators but have never quite been ready to book one. In Allergan’s consumer research, 79% of people said they wished they could preview a treatment’s outcome before deciding. Now they can.

01

First-timers

Try a softened frown line for a few weeks, see how it feels in your own face, and decide about Botox from experience rather than guesswork.

02

An event on the calendar

A wedding, a reunion, a milestone birthday, a photoshoot. Boey can be timed so results arrive for the occasion and fade on their own afterwards.

03

Botox-curious, commitment-shy

If three to four months feels like a long time to live with a result you have never seen, a two to three week preview changes the decision entirely.

04

Worried about looking frozen

The most common hesitation we hear. Because the effect is short, Boey is a low-stakes way to discover that a treated frown line still moves naturally. Refreshed, not frozen is the standard here.

05

Returning after a long break

Patients who stopped treatment years ago and want to reacquaint themselves gently before resuming a maintenance routine.

06

Ready for the next step

Botox Cosmetic® is the only neuromodulator clinically studied for use after Boey. Love the result? Your injector plans the transition, and you keep the same clinic and the same team.

Choosing Your Neurotoxin

Boey vs Botox: different jobs.

Both come from Allergan Aesthetics and both are injected by the same experienced providers at Rejuvenation. The right choice comes down to one question: how long do you want the result to last?

Boey®
Botox®
Toxin type
Botulinum toxin type E
Botulinum toxin type A
Onset
As early as 8 hours; builds over the first few days
3 to 5 days
Full effect
Within about a week
About 2 weeks
Duration
About 2 to 3 weeks
3 to 4 months
Approved areas
Frown lines between the brows
Frown lines, forehead lines, crow’s feet and more, plus medical uses
Best for
A first experience, an event, a preview before committing
Ongoing maintenance and prevention
What comes next
Botox Cosmetic is the only neuromodulator clinically studied for use after Boey
Repeat every 3 to 4 months
Canadian approval
June 2026 (first country in the world)
Decades of clinical use in Canada

General comparison based on Canadian product information. Units of Boey are not interchangeable with units of Botox or any other botulinum toxin product; dosing is determined by your injector. Product selection and expected outcomes are individual and confirmed at your consultation. Also offered at Rejuvenation: Dysport® and Nuceiva®.

The Waitlist

How the waitlist works.

Boey is arriving at Canadian clinics now, and supply will be limited at first. The waitlist puts you at the front of the line at the Rejuvenation clinic of your choice.

01

Join the list

Use the form below or call your clinic. Tell us which Rejuvenation clinic you prefer and write “Boey waitlist” in your message so we can tag your request.

02

We confirm your spot

A cosmetic coordinator confirms your place on the list and answers your questions about candidacy, timing and pricing as details are finalized.

03

First access

When Boey arrives at your clinic, waitlist members are offered the first appointments, in order, before treatment opens to everyone else.

04

Your treatment

A 10 to 20 minute visit with an experienced injector. No downtime. Results may begin within hours and fade naturally over two to three weeks.

Join the waitlist → Call (403) 286-6888
Candidacy

Is Boey right for you?

Most healthy adults with frown lines are candidates. Your consultation confirms the plan before anything is injected.

  • Moderate to severe frown lines between the brows when you concentrate or squint
  • Curious about neuromodulators but not ready for a three to four month commitment
  • An event in the coming weeks where you would like to look rested
  • Good general health; not pregnant or nursing
  • No active skin infection at the injection site and no known allergy to botulinum toxin products
  • Realistic expectations: a short, temporary preview of a smoother brow
Our Clinics

Boey® in Calgary, Edmonton, Vancouver, Okotoks and Oakville.

The waitlist is open for all nine Rejuvenation Dermatology clinics across Alberta, British Columbia and Ontario. Rollout timing will vary by clinic, and waitlist members hear first.

Calgary SouthAlberta
10201 Southport Rd SW #102
Calgary, AB T2W 4X9

Mon 7am to 7pm · Tue and Wed 7am to 8pm · Thu 7am to 7pm · Fri 7am to 5:30pm · Sat 8am to 3:30pm · Sun 9am to 3pm

Join Waitlist(587) 443-9881Directions
Calgary NorthAlberta
130 Country Village Rd NE #405
Calgary, AB T3K 6B8

Mon to Thu 7:30am to 8pm · Fri 7:30am to 5pm · Sat 8am to 3pm · Closed Sun

Join Waitlist(587) 443-9185Directions
Calgary WestAlberta
780 78 Street SW #201
Calgary, AB T3H 3V6

Mon to Thu 7am to 7pm · Fri 7am to 5pm · Closed Sat and Sun

Join Waitlist(825) 401-8588Directions
Calgary Vein & LaserAlberta
10201 Southport Rd SW #225
Calgary, AB T2W 4X9

Mon to Fri 9am to 5pm · Sat call for hours · Closed Sun

Join Waitlist(403) 252-4410Directions
OkotoksAlberta
10 D'Arcy Ranch Dr. #102
Okotoks, AB T1S 5V9

Mon to Fri 9am to 4:30pm · Closed Sat and Sun

Join Waitlist(587) 443-3525Directions
Edmonton DowntownAlberta
10665 Jasper Ave #780
Edmonton, AB T5J 3S9

Mon to Fri 7am to 6pm · Closed Sat and Sun

Join Waitlist(780) 733-0029Directions
Edmonton SouthAlberta
5083 Windermere Blvd #101
Edmonton, AB T6W 0J5

Mon 7am to 7pm · Tue 7am to 8pm · Wed 7am to 7pm · Thu 7am to 8pm · Fri 7am to 7pm · Sat and Sun 9am to 4pm

Join Waitlist(587) 442-9121Directions
Vancouver Coal HarbourBritish Columbia
1055 Canada Pl #62
Vancouver, BC V6C 0C3

Mon to Fri 8am to 4:30pm · Closed Sat and Sun

Join Waitlist(778) 262-0880Directions
OakvilleOntario
2295 Bristol Circle #101
Oakville, ON L6H 6P8

Mon to Fri 8am to 5pm · Sat by appointment · Closed Sun

Join Waitlist(289) 291-2955Directions
Questions

Frequently asked questions about Boey.

What is Boey?

Boey® (trenibotulinumtoxinE) is an injectable neurotoxin made by Allergan Aesthetics, the makers of Botox. It is a botulinum toxin type E, and Health Canada authorized it in June 2026 for the temporary improvement of moderate to severe frown lines between the eyebrows in adults. Canada was the first country in the world to approve it.

How is Boey different from Botox?

Both relax the small muscles that create frown lines, but Boey is a serotype E toxin and Botox is serotype A. Boey acts faster and clears sooner: results may begin within hours and fade in about two to three weeks, while Botox takes several days to begin working and lasts three to four months. Boey is approved for frown lines only; Botox is approved for frown lines, forehead lines, crow’s feet and several medical uses.

How fast does Boey work?

In the clinical trials some patients saw a visible change as early as 8 hours after treatment, and most responders reached the trial’s threshold by day seven. Expect results to build over the first few days rather than appear all at once.

How long does Boey last?

About two to three weeks. In the trials, frown lines returned to their starting point between days 14 and 21. The short duration is by design: Boey is meant to be a preview rather than a maintenance treatment.

Can I have Botox after Boey?

Yes. Botox Cosmetic® is the only neuromodulator clinically studied for use after Boey. If you like your Boey result, your injector can plan the transition to Botox at the same clinic.

What areas can Boey treat?

Health Canada has authorized Boey for frown lines between the eyebrows (glabellar lines) only. For forehead lines, crow’s feet, jawline slimming or medical uses such as migraines and excessive sweating, Botox and Dysport remain the options.

Is Boey safe? What are the side effects?

Boey was studied in two placebo-controlled Phase 3 trials with 947 patients. The most common side effects were headache and injection-site pain or redness, each reported no more often than with placebo. Eyelid or brow drooping was uncommon. As with all botulinum toxin products there is a rare risk of the effect spreading beyond the treated area, so your injector reviews your health history before treatment.

Does a Boey treatment hurt?

Most patients describe neuromodulator injections as a brief, mild pinch. Boey uses a very fine needle, the visit takes only minutes, and a topical numbing cream can be applied beforehand if you prefer.

When will Boey be available at Rejuvenation Dermatology?

Health Canada authorized Boey in June 2026 and Allergan Aesthetics is now rolling it out to Canadian clinics. Timing varies by clinic. Joining the waitlist is the fastest way to find out when your Rejuvenation clinic has treatment dates, and waitlist members are offered the first appointments.

How much does Boey cost?

Pricing will be confirmed before launch. Waitlist members receive pricing details first, before they are published, along with any introductory offers.

Be First in Line

Join the Boey waitlist today.

Tell us which Rejuvenation Dermatology clinic you prefer in Calgary, Edmonton, Vancouver, Okotoks or Oakville, and write “Boey waitlist” in your message. We will be in touch as soon as your clinic has dates.

Join the waitlist → Call (403) 286-6888 →
Calgary North, South & WestCalgary Vein & LaserOkotoksEdmonton South & DowntownVancouver Coal HarbourOakville

This page is for general information about Boey® (trenibotulinumtoxinE), a prescription medicine authorized by Health Canada for the temporary improvement in the appearance of moderate to severe frown lines (glabellar lines) in adults. It is not medical advice. Boey is a medical treatment with risks as well as benefits; onset, degree and duration of results vary between individuals. Suitability and dosing are determined at a personal consultation with a qualified provider.

Important safety information. Boey should not be used by anyone with an infection at the planned injection site or a known allergy to any botulinum toxin product. Adverse reactions reported in clinical trials included headache, injection-site pain and redness, and, uncommonly, eyelid or brow drooping. As with all botulinum toxin products, the effect can in rare cases spread away from the treated area and cause symptoms such as muscle weakness, drooping eyelids, double or blurred vision, or difficulty swallowing or breathing; seek medical attention immediately if any of these occur. One unit of Boey is not the same as one unit of any other botulinum toxin product. Tell your provider about all medical conditions, medications and previous neuromodulator treatments. Boey®, Botox® and Botox Cosmetic® are trademarks of Allergan Aesthetics, an AbbVie company.

Join the Boey Waitlist

Be among the first patients treated with Boey® at Rejuvenation Dermatology. Tell us which clinic you prefer (Calgary North, South or West, Calgary Vein & Laser, Okotoks, Edmonton Downtown or South, Vancouver Coal Harbour, or Oakville) and write “Boey waitlist” in your message. A cosmetic coordinator will confirm your spot and reach out as soon as your clinic has treatment dates.

Learn More About Neuromodulators

Boey is new, but the questions behind it are not. Start with our guides to how neuromodulators work, what to expect at a first appointment, and how to keep results looking natural.